Cholesterol Drugs Overview

Drugs used to treat cholesterol are divided into different groups: those that lower LDL cholesterol and those that raise HDL cholesterol or lower triglycerides. It helps to know how the body processes cholesterol in order to understand how cholesterol drugs work.

Cholesterol comes from two sources: diet and the liver. When cholesterol and triglycerides from fat are consumed in the diet, they go to the liver, where they are processed, repackaged, and sent back into the bloodstream for distribution by LDLs to cells that need them.

Cholesterol drugs
The many different types of cholesterol drugs might be used to lower
bad cholesterol, raise good cholesterol or lower triglycerides.

In addition, the liver produces triglycerides, which are carried by VLDLs, along with some cholesterol, to cells where the triglycerides can be stored. When the triglycerides are deposited, mostly cholesterol is left over, turning the VLDLs into plain old LDLs.

Certain cells in the body have what are called receptors on them. These receptors pull cholesterol out of LDLs circulating in the blood and into the cell. When the receptors have taken up all the cholesterol they can manage, the number of receptors shrinks to decrease the amount of cholesterol entering the cell. Any unused LDL cholesterol then remains in the blood, which the LDLs subsequently deposit in the walls of your arteries as plaque.

Drugs that lower LDL cholesterol do so by influencing the balance between production and removal of cholesterol in the body. These drugs work in a fairly predictable fashion. Drugs that raise HDL cholesterol, unfortunately, don't work in a similar predictable fashion. Various other drugs lower triglycerides or other lipoproteins.

One common form of cholesterol medication is statins. Find out what they are and how they work on the next page.

For more information on cholesterol, see:
  • Cholesterol Levels: We all know there's "good" and "bad" cholesterol. Find out why you need more of one kind of cholesterol and less of the other.
  • Causes of High Cholesterol: Diet and DNA are the main sources of cholesterol. Learn why the numbers might be high in your case.
  • How to Lower Cholesterol: Like many conditions, eating right and exercising will control cholesterol. Learn what that means for you.
  • How Cholesterol Works: Cholesterol is essential to the body. Find out why we need it and how much is too much.

This information is solely for informational purposes. IT IS NOT INTENDED TO PROVIDE MEDICAL ADVICE. Neither the Editors of Consumer Guide (R), Publications International, Ltd., the author nor publisher take responsibility for any possible consequences from any treatment, procedure, exercise, dietary modification, action or application of medication which results from reading or following the information contained in this information. The publication of this information does not constitute the practice of medicine, and this information does not replace the advice of your physician or other health care provider. Before undertaking any course of treatment, the reader must seek the advice of their physician or other health care provider.