What is Cholesterol?
Cholesterol is a waxy, fat-like compound that belongs to a class of molecules
called
steroids. It's found in many
foods, in your bloodstream and in all
your body's
cells. If you had a handful of cholesterol, it might feel like a
soft, melted candle. Cholesterol is essential for:
- Formation and maintenance of cell membranes (helps the cell to resist changes in temperature and protects and insulates nerve fibers)
- Formation of sex hormones (progesterone, testosterone, estradiol, cortisol)
- Production of bile salts, which help to digest food
- Conversion into vitamin D in the skin when exposed to sunlight.
The formation of cholesterol involves a series of complicated biochemical
reactions that begin with the widespread 2-carbon molecule Acetyl CoA: Acetyl
CoA (C2) --> mevalonate (C6) --> isopentenyl pyrophosphate (C5) -->
squalene (C30) --> cholesterol (C27). Cholesterol is made primarily in your
liver (about 1,000 milligrams a day), but it is also created by cells lining the small intestine and by individual cells in the body.

Most of the body's cholesterol is manufactured in the
liver.
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