Diabetes and Fibrates

Unlike statins, these drugs (sometimes called fibric acid derivatives) aren't known for their LDL-lowering prowess. However, fibrates stimulate an enzyme that breaks down fats, so they lower triglycerides very effectively -- by as much as 50 percent in some trials. Fibrates also produce a respectable increase in HDL cholesterol, more on the order of 10 or 15 percent.

Although they are considered safe, fibrates can cause gastrointestinal distress and may increase the risk of developing gallstones. If you're taking a statin, adding a fibrate may increase the risk of muscle pain or weakness.

Learn how resins work to lower cholesterol -- and learn their side effects -- in the next section.

For more information on diabetes, and its effect on cholesterol and the heart, try the following links:

  • Diabetes and Heart Disease explains the relationship between these two conditions.
  • Diabetes Symptoms covers the diverse signs of the disease, from increased thirst and hunger to sudden weight loss.
  • To learn more about diabetes in general, including diagnosis, causes, symptoms, and treatment, visit our main Diabetes page.
  • For more information on cholesterol and its effect on your health, read How Cholesterol Works.

This information is solely for informational purposes. IT IS NOT INTENDED TO PROVIDE MEDICAL ADVICE. Neither the Editors of Consumer Guide (R), Publications International, Ltd., the author nor publisher take responsibility for any possible consequences from any treatment, procedure, exercise, dietary modification, action or application of medication which results from reading or following the information contained in this information. The publication of this information does not constitute the practice of medicine, and this information does not replace the advice of your physician or other health care provider. Before undertaking any course of treatment, the reader must seek the advice of their physician or other health care provider.