Osteoarthritis medications come in various forms, including tablets, capsules, and topical creams. In order to use them safely, follow the instructions on the printed prescription label. You can also ask your pharmacist about how to take your medication. Your pharmacist or doctor will also tell you which foods and other medications you should avoid. If you have any questions or don't understand the directions, be sure to call your doctor or pharmacist. Ask if there is any written information about the medication that you can take home.