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What Do I Need to Know About Statins to Lower Cholesterol?

Possible Drug Interactions With Statins

Make sure your doctor is aware of all the medicines that you are taking before you start any new medicines. Also, ask your pharmacist for a complete list of possible interactions with the statin medicine your doctor prescribes. Statins may interact with the following:

  • alcohol
  • antacids
  • the cholesterol medicines bile acid resins, gemfibrozil, and nicotinic acid
  • cyclosporine, which suppresses the immune system
  • the antibiotics erythromycin and rifampin
  • the ulcer medicines cimetidine, ranitidine, and omeprazole
  • propranolol, used for blood pressure or heart conditions
  • oral contraceptives
  • digoxin, a heart medicine
  • warfarin, a blood thinner
  • the antifungal medicines fluconazole, itraconazole, and ketoconazole
If you take atorvastatin, your skin may be more sensitive to sunlight. So take care not to get sunburned.

If you take lovastatin, avoid taking it with grapefruit juice. It may interact dangerously with your medicine, causing higher levels of lovastatin in your blood. The potential increase is unpredictable and may worsen side effects.