Like HowStuffWorks on Facebook!

Health | Diseases & Conditions | Rare Diseases

Rare diseases may not be common, but they are no less painful or difficult than conditions you've heard of. Learn about the causes and symptoms of rare diseases as well as how patients can find treatments for their unusual conditions.


The Ultimate Diagnosis Quiz

The Ultimate Diagnosis Quiz

Think you know all there is to know about rare medical disorders? Play doctor and find out with this quiz! See more »

Fact or Fiction: Eradicated Diseases

Fact or Fiction: Eradicated Diseases

This eradicated disease quiz will test your knowledge of some of the diseases that science has defeated. Test yourself with this eradicated disease quiz. See more »

Bizarre Medical Conditions Quiz

Bizarre Medical Conditions Quiz

The bizarre medical conditions quiz tests your knowledge of some almost unbelievable conditions. Learn more with the bizarre medical conditions quiz. See more »

10 Bizarre Medical Conditions

10 Bizarre Medical Conditions

Bizarre medical conditions have baffling symptoms and often no cure. Take a look at these 10 bizarre medical conditions that have and do occur. See more »

What are the world's rarest diseases?

What are the world's rarest diseases?

The world's rarest diseases may affect few people or may exist solely in a lab. Learn about the world's rarest diseases and what makes a disease rare. See more »

12 Deadly Diseases Cured in the 20th Century

12 Deadly Diseases Cured in the 20th Century

Diseases like polio and smallpox took countless lives before a cure was found. Read our list of 12 diseases that were cured in the 20th century. See more »