Warts can be stubborn. For the persistent ones, you may have to take stronger measures. Surgery is always a possibility, although it can cause scarring. Surgery with CO2 or electric lasers is becoming more common for warts that haven't responded to other therapies. Once the laser has attacked the wart and caused it to burn, your body's immune system will handle the rest. Pulsed dye lasers are the only type of surgical treatment that don't usually leave a scar.
Besides lasers, we have needles.
- Electric needle. This is the needle version of the CO2 laser (and it can similarly cause scarring).
- Immunotherapy. With this therapy, foreign bodies are injected into the wart. The immune system raises the alarm and sends cells to fight the invader, getting rid of the wart at the same time. (It can't be any old foreign body -- it has to be one that the immune system will recognize.)
- Needling. Performed most often on plantar warts, this process involves sticking a needle into the wart 100-200 times, in the hopes that it will trigger an immune response.