While letting nature take its course is generally the best treatment for acute bronchitis, complications can sometimes occur, so you'll need to stay alert for signs that it's time to see your doctor. The most worrisome complications include pneumonia, sinus infection and ear infection, all of which need to be treated with prescription antibiotics. Signs that one or more of these complications may be present include a persistent high fever (not a typical characteristic of bronchitis), severe shortness of breath, prolonged coughing spells or a cough that lasts more than four to six weeks, severe chest pain, pain behind the eyes or ear pain. Be on the lookout for blood in your sputum or sputum that changes dramatically in color or consistency, and report it to your doctor. In addition, tell your doctor if you suffer frequent bouts of bronchitis, since you may be suffering from a more serious respiratory problem that requires medical treatment.