Benefits of Fenugreek


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  • Gupta A, Gupta R, Lal B. Effect of Trigonella foenum-graecum (fenugreek) seeds on glycaemic control and insulin resistance in type 2 diabetes mellitus: a double blind placebo controlled study.  J Assoc Physicians India. 2001 Nov;49:1057-61.
  • Madar Z, Abel R, Samish S, Arad J. Glucose-lowering effect of fenugreek in non-insulin dependent diabetics.  Eur J Clin Nutr. 1988 Jan;42(1):51-4.
  • Vijavakumar MV, et al.  The hypoglycaemic activity of fenugreek seed extract is mediated through the stimulation of an insulin signalling pathway. Br J Pharmacol. 2005 Sep;146(1):41-8.
  • Lu FR, et al.  Clinical observation on trigonella foenum-graecum L. total saponins in combination with sulfonylureas in the treatment of type 2 diabetes mellitus.  Chin J Integr Med. 2008 Mar;14(1):56-60.
  • Sharma, R.D., et al.  Effect of Fenugreek Seed on Blood Glucose and Serum Lipids in Type I Diabetes. European Journal of Clinical Nutrition, 1990;44:301-306.
  • Sowmva P, Rajyalakshmi P. Hypocholesterolemic effect of germinated fenugreek seeds in human subjects.  Plant Foods Hum Nutr. 1999;53(4):359-65.
  • Shishodia S, Aggarwal BB.  Diosgenin inhibits osteoclastogenesis, invasion, and proliferation through the downregulation of Akt, I kappa B kinase activation and NF-kappa B-regulated gene expression.  Oncogene. 2006 Mar 9;25(10):1463-73.
  • Kaviarasan S, et al.  Polyphenol-rich extract of fenugreek seeds protect erythrocytes from oxidative damage.  Plant Foods Hum Nutr. 2004 Fall;59(4):143-7.
  • Kaviarasan S, et al. Fenugreek (Trigonella foenum graecum) seed extract prevents ethanol-induced toxicity and apoptosis in Chang liver cells. Alcohol Alcohol. 2006 May-Jun;41(3):267-73. Epub 2006 Mar 30.
  • Srinivasan S, et al.  Diosgenin targets Akt-mediated prosurvival signaling in human breast cancer cells.  Int J Cancer. 2009 Aug 15;125(4):961-7.
  • Hibasami H, et al. Protodioscin isolated from fenugreek (Trigonella foenumgraecum L.) induces cell death and morphological change indicative of apoptosis in leukemic cell line H-60, but not in gastric cancer cell line KATO III. Int J Mol Med. 2003 Jan;11(1):23-6.
  • Flammang AM, et al. Genotoxicity testing of a fenugreek extract. Food Chem Toxicol. 2004 Nov;42(11):1769-75.