Benefits of Milk Thistle

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  • Ferenci, P. (1989). Randomized controlled trial of silymarin treatment in patients with cirrhosis of the liver. J Hepatol, 9(1):105-13.
  • Feher, J. (1989). Liver-protective action of silymarin therapy in chronic alcoholic liver diseases. Orv Hetil, 130(51):2723-7.
  • Salmi, H.A., Sarna, S. (2002). Effect of silymarin on chemical, functional, and morphological alterations of the liver. Scand J Gastroenterol, 17:517-520,1982.
  • Jacobs, B.P. (2002). Milk thistle for the treatment of liver disease: A systematic review and meta-analysis. Am J Med, 113(6):506-15.
  • Pares, A. (1998). Effects of silymarin in alcoholic patients with cirrhosis of the liver: Results of a controlled, double-blind, randomized and multicenter trial. J Hepatol, 28(4):615-21.
  • Zhao, J., Lahiri-Chatterjee, M., Sharma, Y., Agarwal, R. (2000). Inhibitory effect of a flavonoid antioxidant silymarin on benzoyl peroxide-induced tumor promotion, oxidative stress and inflammatory responses in sencar mouse skin. Carcinogenesis, 21:811-816.
  • Zhao, J., Sharma, Y., Agarwal, R. (1999). Significant inhibition by the flavonoid antioxidant silymarin against 12-O-tetradecanoylphorbol 13-acetate-caused modulation of antioxidant and inflammatory enzymes, and cyclooxygenase 2 and interleukin-1alpha expression in Sencar mouse epidermis: Implications in the prevention of stage I tumor promotion. Mol Carcinog, 26:321-333.
  • Lahiri-Chatterjee, M., Katiyar, S.K., Mohan, R.R., Agarwal, R. (1999). A flavonoid antioxidant, silymarin, affords exceptionally high protection against tumor promotion in the SENCAR mouse skin tumorigenesis model. Cancer Res, 59:622-632.
  • Wright, T.I. (2006). Chemoprevention of nonmelanoma skin cancer. J Am Acad Dermatol, 54(6):933-46; quiz 947-50.
  • Pinnell, S.R. (2003). Cutaneous photodamage, oxidative stress, and topical antioxidant protection. J Am Acad Dermatol, 48(1):1-19; quiz 20-2.
  • Bhatia, N., Agarwal, C., Agarwal, R. (2001). Differential responses of skin cancer-chemopreventive agents silibinin, quercetin, and epigallocatechin 3-gallate on mitogenic signaling and cell cycle regulators in human epidermoid carcinoma A431 cells. Nutr Cancer, 39:292-299.
  • Rainone, F. (2005). Milk thistle. Am Fam Physician, 72(7):1285-8.