The flu is often accompanied by a high fever that can range from 102 to 106 degrees Fahrenheit. You can count on a doozy of a headache, too. Lowering the fever will help prevent dehydration and will cut down on the severe, shaking chills associated with fever. On the other hand, since a fever may actually help your body fight the bug, you may want to try to let the fever run its course if it's safe for you to do so. Aspirin and ibuprofen are generally better at easing aches and pains; acetaminophen is most effective at fighting fever. For a list of precautions to take when using over-the-counter analgesics, click here.