Not everyone is a good candidate for the drugs.
Prescription drugs and nicotine replacement are not recommended for several groups of people across the board. Most pregnant women and nursing mothers are advised to steer clear of prescription drugs and nicotine replacement. But Dr. Schroeder says that in some cases, with a doctor's supervision, it might be better for these women to use a drug than to keep smoking. "None of these medicines is going to be as damaging as the pregnant women who keep smoking," he says.
For other groups, the guidelines are more clear-cut. The antidepressants, like Zyban, are absolutely off-limits to people with seizure disorders or a history of manic episodes, bipolar disorder, bulimia or anorexia [source: GlaxoSmithKline].
People with heart disease should be cautious about starting nicotine replacement therapy at high doses.