Does Metformin make you more fertile?


Can Metformin alleviate anovulation?

Ovulation is not just the process by which an ovary releases an egg; it's marked by the release of a mature egg. An immature ovum causes a cycle that is anovulatory [source: Hernandez-Rey]. Anovulatory cycles or anovulation ensure infertility.

The causes of anovulation can range anywhere from problem with the hypothalamus to the early onset of menopause [source: Stanford]. Polycystic ovarian syndrome is one potential cause [source: Sherbahn]. A woman diagnosed with PCOS can be given various instructions and/or medications by her doctor. Metformin is one such medication. Clomid may be prescribed in conjunction with Metformin to treat PCOS. Once normal insulin levels are seen and menstruation occurs at regular intervals, anovulation may be alleviated [source: Labor of Love]. Those factors increase the chances of a woman becoming pregnant.

Fertility drugs, such as those that hyperstimulate the ovaries, have led to an increase in multiple births [source: Science Daily]. Metformin, however, does not fall into the category of COH (controlled ovarian stimulation) drugs. Since its purpose is to restore insulin production to normal levels and treat PCOS, it has not been linked to an increase in pregnancies involving twins, triplets and other births of more than one child. This fact makes Metformin different than most fertility medications [source: Labor of Love].

Metformin is not an across-the-board treatment for infertility. It has been proven effective in specific cases involving medical issues related to high blood sugar, insulin resistance and polycystic ovarian syndrome. A qualified physician can determine its appropriateness and whether it should be used alone or in combination with other treatments.

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Sources

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