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20 Diseases You've Probably Never Heard Of


8
Hailey-Hailey Syndrome
Hailey-Hailey syndrome is characterized by blisters and lesions.
Hailey-Hailey syndrome is characterized by blisters and lesions.
©iStockphoto.com/mahlrovitz

This genetic disease is characterized by blisters and lesions that may come and go, usually healing without scarring. It becomes apparent after puberty and occurs because of a mutation in a gene responsible for production of a protein essential for good skin health.

Also known as benign chronic familial pemphigus or HHD, Hailey-Hailey occurs due to a mutation in a specific gene that creates a protein that is essential for the proper health of skin, according to the NORD Web site. The disorder becomes apparent after puberty and symptoms can develop at any age.

Read More About the Disease From NORD


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