Like HowStuffWorks on Facebook!

Excessive Underarm Sweating

Medications for Excessive Underarm Sweating

You've tried a variety of regular deodorants, but nothing seems to tame your axillary hyperhidrosis. Before you give up, you might want to try some other products. For example, your physician can prescribe an antiperspirant made from aluminum chloride. These prescription deodorants work by forming gel plugs in the sweat glands, which help to prevent excessive sweating. Recent studies have even shown that aluminum chloride gel works effectively without as many side effects, such as rashes or itchiness, as previous treatment options [source: Bankhead].

Another option is an oral medication; anticholinergic drugs block acetylcholine -- the chemical that stimulates sweat glands to produce sweat. However, anticholinergic drugs don't only affect acetylcholine -- they affect your whole system, and often carry side effects such as dry mouth, blurry vision and dizziness [source: Mayo Clinic].

A third option is botulinum toxin -- more commonly known as Botox. Studies have shown that intradermal injections of Botox -- injections that go in or between the layers of your skin -- can provide long-term relief from excessive sweating. In early studies, out of 182 research volunteers, 92 percent needed four or fewer Botox injections over a two-year period [source: WebMD]. However, with an out-of-pocket price tag of $500 to $1,000 per treatment, Botox can be prohibitive if your insurance doesn't cover it for axillary hyperhidrosis [source: International Hyperhidrosis Society].

You might not have to head to the pharmacy or the doctor's office to treat your excessive sweating. Read on to learn about home remedies you can try to calm your overactive sweat glands.