Unfortunately, there are no vaccines or cures for fifth disease. Because it is a virus, antibiotics aren't used to treat the infection [Web MD: Fifth].
For the most part, the effects of fifth disease will go away on their own with plenty of rest, fluids and pain relievers to address any soreness or fever. In children, the disease will usually go away after seven to 10 days, though it may last a couple of weeks for adults or in severe cases. Once a person is showing the rash symptoms of fifth disease, he or she should no longer be contagious. In other words, there's no need to hide or quarantine yourself [source: Center for Disease Control].
When people with severe anemia or immune deficiency contract fifth disease, they might have to go to the hospital so doctors can monitor the infection and prevent it from getting worse. In severe cases, patients may receive blood transfusions or antibodies to help fight the infection [Mayo Clinic: Parvovirus].
For pregnant women who contract fifth disease, the doctor may want to schedule more frequent checkups and ultrasounds to make sure the baby remains healthy [source: Center for Disease Control]. If the doctor is worried about the baby becoming anemic or having any heart-related issues, he may recommend transfusions or other medications at that time [Mayo Clinic: Parvovirus].
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