Howard Hughes -- known for his wealth, movie production and aviation skills in the early and mid 1900s -- was always in the spotlight for one thing or another. But, ultimately, he is also remembered for his struggle with obsessive compulsive disorder, a condition that causes a combination of unnatural obsessions, anxiety and compulsions, which usually are acted out in repetitive behaviors. Unfortunately, Hughes' OCD led to isolation, increased drug use and his own death, according to the British Broadcasting Corporation. Notably, his obsession with cleanliness and reputation as a "germaphobe" were evident in his daily life and interactions with his employees. In one repetitive routine, he made his workers use several facial tissues and rounds of hand-washing just to fetch his hearing-aid cord. His career and personal battle with the disorder inspired the 2004 Oscar-winning film "The Aviator." Anxiety is also no stranger to this next celebrity.
Click onward to see which cooking icon has fought panic attacks for years.